Long-Term Autoimmune Inflammatory Rheumatic Outcomes of COVID-19 : A Binational Cohort Study
An erratum to this article was published (Ann Intern Med, Jul 2024 ↗)
Authors' conclusion
SARS-CoV-2 infection was associated with increased risk for incident AIRD compared with matched patients without SARS-CoV-2 infection or with influenza infection. The risk for incident AIRD was higher with greater severity of acute COVID-19.
Study context
- Population
- Patients aged 20 years or older in nationwide claims-based databases in South Korea (K-COV-N cohort) and Japan (JMDC cohort)10,027,506 Korean, 12,218,680 Japanese
- Exposure
- COVID-19 vs uninfected controls and vs influenza-infected controls
- Outcome
- Onset of AIRD (per ICD-10 codes) after COVID-19 or influenza infection or matched index date
- Follow-up
- 1, 6, and 12 months
Methodological detailsbinational, longitudinal, propensity-matched, nationwide claims-based databases
- Binational
- Longitudinal
- Propensity-matched
- Nationwide claims-based databases
Main finding
As reported in the abstract
Incident AIRD beyond the first 30 days after infection (Korean cohort, after propensity score matching)
Adjusted hazard ratio (95% CI)
COVID-19vs Uninfected
1.25(1.18–1.31)
COVID-19vs Influenza
1.30(1.02–1.59)
Observational data: associations, not effects.
Further findings
Incident AIRD by severity of acute COVID-19
- The risk for incident AIRD was higher with more severe acute COVID-19
Japanese cohort
- Similar patterns were observed in the Japanese cohort
Original publication
Long-Term Autoimmune Inflammatory Rheumatic Outcomes of COVID-19 : A Binational Cohort Study. Ann Intern Med. Published 5 March 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →