Kihon Checklist validation in patients with rheumatoid arthritis: Italian translation, cross-cultural adaptation, and evaluation of the validity in comparison to two frailty screening tools based on the Fried phenotype and deficit accumulation model
Authors' conclusion
All the tools examined were useful and reflected the definition of frailty, however, the KCL was the most suitable since it is self-administered and might enable interventions in RA patients.
Study context
- Population
- Adult rheumatoid arthritis (RA) patients
- Participants
- 219 patients
- Comparison
- Kihon Checklist (KCL) vs Comprehensive Rheumatologic Assessment of Frailty (CRAF) vs Survey of Health, Ageing and Retirement in Europe Frailty Instrument (SHARE-FI) for identifying frailty
- Outcome
- Discriminant validity: differences in AUC-ROCs vs CHS criteria in identifying frailty
Methodological detailscross-sectional, Italian translation and cross-cultural adaptation, Cardiovascular Health Study (CHS) criteria as external gold standard
- Cross-sectional
- Italian translation and cross-cultural adaptation
- CHS criteria as external gold standard
Performance
As reported in the abstract
Frailty identification vs CHS criteria
| Test or model | Value | Optimal cut-off | Sensitivity | Specificity | Positive likelihood ratio |
|---|---|---|---|---|---|
| KCL | 7 | 93.3% | 90.8% | 10.15 | |
| CRAF | 35.6% | ||||
| SHARE-FI | 16.0% |
Value
KCL— not stated in the abstract
CRAF35.6%
SHARE-FI16.0%
Optimal cut-off
KCL7
CRAF— not stated in the abstract
SHARE-FI— not stated in the abstract
Sensitivity
KCL93.3%
CRAF— not stated in the abstract
SHARE-FI— not stated in the abstract
Specificity
KCL90.8%
CRAF— not stated in the abstract
SHARE-FI— not stated in the abstract
Positive likelihood ratio
KCL10.15
CRAF— not stated in the abstract
SHARE-FI— not stated in the abstract
Original publication
Kihon Checklist validation in patients with rheumatoid arthritis: Italian translation, cross-cultural adaptation, and evaluation of the validity in comparison to two frailty screening tools based on the Fried phenotype and deficit accumulation model. Clin Exp Rheumatol. Published 30 August 2022. doi:10.
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