Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder
Authors' conclusion
Short course prednisolone on first day of each episode and its dramatic and meaningful response in our patients, introduce a new, effective, fast, and inexpensive regimen of therapy in patients with JIRP.
Study context
- Population
- Children diagnosed with JIRP, 1 January 2002 to 29 February 2023
- Participants
- 10 children
- Exposure
- Short course prednisolone vs natural course of disease
- Prednisolonen = 10
- Outcome
- Response to treatment on first day of prednisolone vs natural course
- Follow-up
- First day of administration
Methodological detailsconsecutive case series, retrospective chart review
- Consecutive case series
- Retrospective chart review
Main finding
As reported in the abstract
- All patients showed a dramatic response to treatment on the first day of prednisolone
- Prednisolone vs natural course of disease: P Value 0.005
Observational data: associations, not effects.
Further findings
Demographics and disease course
- Male
- 70%
- Median age of onset
- 5 years
- Duration of episodes
- 5 days
- Mean course of disease
- 3.8 years
- Average follow-up
- near 10 years
Additional accompanying autoimmune disorder · ten years follow up
- No additional accompanying autoimmune disorder
Original publication
Juvenile idiopathic recurrent parotitis (JIRP) treated with short course steroids, a case series study and one decade follow up for potential autoimmune disorder. Pediatr Rheumatol Online J. Published 4 January 2024. doi:10.
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