Juvenile Dermatomyositis in Afro-Caribbean children: a cohort study in the French West Indies
Authors' conclusion
They had higher rate of calcinosis and similar respiratory involvement. Overall outcomes during childhood were similar to North America and European countries.
Study context
- Population
- Afro-Caribbean children with Juvenile Dermatomyositis (JDM) followed up in the French West Indies, 2000–202323 year-period
- Participants
- 21 children
- Outcome
- Clinical and biological features during childhood
Methodological detailsmultiple-source case ascertainment, ILAR criteria
- Multiple-source case ascertainment
- ILAR criteria
Main finding
As reported in the abstract
- Median age at onset (Range: 2.5-13.9)
- 8.1 years
- Median follow up (Range: 2-19)
- 8 years
- Dysphagia at onset
- 14/21
- Respiratory involvement
- 33%
- Specific autoantibodies, most frequently anti-Mi-2 (13 patients)
- 58%
- Median number of flares during childhood (1-9)
- 3
- Calcinosis lesions during childhood
- 76%
Observational data: associations, not effects.
Further findings
Number of flares, boys vs girls · childhood
P = 0.04
Needing more than one background therapy, boys vs girls · childhood
P = 0.03
Original publication
Juvenile Dermatomyositis in Afro-Caribbean children: a cohort study in the French West Indies. Pediatr Rheumatol Online J. Published 7 October 2023. doi:10.
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