Inflammatory myopathies

Investigating the disparities among drug categories in drug-induced dermatomyositis: A systematic review

Semin Arthritis RheumPublished Systematic review of published case reports

Authors' conclusion

In conclusion, our review consolidates the current literature on DIDM, highlighting the evolving spectrum of medications and elucidating the differences in clinical manifestations, laboratory findings, and underlying mechanisms.

Study context

Population
Published cases of drug-induced dermatomyositis (DM) (drug-induced dermatomyositis (DIDM)), English literature
Participants
69 published DIDM cases
Comparison
Biologics vs traditional drugs as causes of drug-induced DM
  • Biologicsn = 33
  • Traditional drugsn = 36reference
Outcome
Published DIDM cases by causative drug category (biologics vs traditional drugs) and history of malignancy
Methodological detailsliterature search of Pubmed, EMBASE and MEDLINE, English literature
  • Literature search of Pubmed, EMBASE and MEDLINE
  • English literature

Pooled result

As reported in the abstract

Biologics

33

events

Traditional drugs

36

events

Total published DIDM cases documented
69
DIDM cases with a previous history of malignancies
41

Original publication

Investigating the disparities among drug categories in drug-induced dermatomyositis: A systematic review. Semin Arthritis Rheum. Published 27 May 2024. doi:10.1016/j.semarthrit.2024.152478

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