Intracluster correlation coefficients in osteoarthritis cluster randomized trials: A systematic review
Authors' conclusion
Despite CONSORT statement recommendations for reporting cluster RCTs, few OA trials reported the observed ICC.
Study context
- Population
- Knee/hip osteoarthritis (OA) cluster randomized clinical trials (RCTs) published from 2012 to September 2022 (Cochrane Central Register of Controlled Trials)
- Participants
- 20 cluster RCTs
- Outcome
- Proportion of cluster RCTs that reported observed intracluster correlation coefficients (ICCs); observed ICC values
Pooled result
As reported in the abstract
Trials reporting the observed ICC for at least one outcome
- Trials reporting observed ICC
- 5 (25%)
- ICC values, pain outcomes
- 0, 0.01, 0.18
- ICC values, physical function outcomes
- 0, 0.06, 0.13 (knee)/0.27 (hip)
- ICC, WOMAC total
- 0.02, 0.02
- ICC, symptoms of anxiety/depression
- 0.22
- ICC, disability
- 0
- ICC, global change
- 0
Further pooled results
Trials with observed ICC larger than ICC used for sample size calculation (underpowered)
- One out of four trials
- 25%
Original publication
Intracluster correlation coefficients in osteoarthritis cluster randomized trials: A systematic review. Osteoarthritis Cartilage. Published 17 September 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →