Lupus & antiphospholipid syndrome
International development and validation of a multilingual bank of items for the self-assessment of essential knowledge by systemic lupus erythematosus patients: the systemic lupus erythematosus (SLE) Knowledge Assessment score (SLAKE)
Authors' conclusion
SLAKE is a valid, multilingual, digital self-assessment tool that effectively measures essential SLE knowledge.
Study context
- Population
- SLE participants1,120 [94.8%] women
- Participants
- 1,182 participants
- Outcome
- SLAKE score (total knowledge, maximum 44 points, and 11 specific domains)
Methodological detailsinternational, multilingual (19 languages), digital self-assessment, multi-step process with healthcare professionals (HCPs) and patient representatives
- International
- Multilingual (19 languages)
- Digital self-assessment
- Multi-step process with HCPs and patient representatives
Performance
As reported in the abstract
SLAKE score
- Median total SLAKE score (IQR 34-40), of a maximum of 44 points
- 37
- Significant positive association with SLE duration
- p= 0.006
- Significant positive association with previous participation in a patient education course or patient training for lupus
- p< 0.0001
- Significant positive association with education level
- p< 0.0001
- No association with age
- p= 0.48
- No association with gender
- p= 0.39
Original publication
International development and validation of a multilingual bank of items for the self-assessment of essential knowledge by systemic lupus erythematosus patients: the SLE Knowledge Assessment score (SLAKE). Rheumatology (Oxford). Published 12 December 2025. doi:10.
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