Intensive training programme for ultrasound-guided minimally invasive synovial tissue biopsy on knees and wrists in different phases of inflammation
Authors' conclusion
This intensive training programme develops advanced skills in the performance of US-guided ST biopsy on knees and wrists, yielding high-quality specimens available for basic and translational studies on inflammatory joint diseases.
Study context
- Population
- Active or remission RA patients undergoing ultrasound (US)-guided synovial tissue biopsy of knees and wrists
- Participants
- 328 synovial tissue (ST) biopsy procedures
- Exposure
- Trainees vs trainers performing US-guided synovial tissue biopsy
- Traineesn = 9
- Outcome
- Rate of informative samples (sample representativity assessed by histology)
Methodological detailssingle-centre, 4-month programme with four sequential phases
- Single-centre
- 4-month programme with four sequential phases
Main finding
As reported in the abstract
Informative samples, active wrists (phase 3)
P = 0.06
Observational data: associations, not effects.
Further findings
Trainees' informative samples, autonomous performance (phase 4)
- Active knees
- 91.9%
- Active wrists
- 90.9%
- Remission knees (lower), p=0.0089
- 77.6%
Trainees' expectations
- Expected procedure-related invasiveness and pain infliction decreased; active wrists and remission knees still perceived as moderately difficult
Safety
- Procedures performed by trainees did not affect patient tolerability
Original publication
Intensive training programme for ultrasound-guided minimally invasive synovial tissue biopsy on knees and wrists in different phases of inflammation. RMD Open. Published 13 February 2024. doi:10.
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