Rheumatoid arthritis

The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis

Arthritis Res TherPublished Proof-of-concept study

Authors' conclusion

The access route through the anatomical snuff box in US-guided synovial biopsies of the RC joint allows for a safe and targeted collection of adequate tissue samples.

Study context

Population
Consecutive patients with active chronic arthritis of the wrist
Participants
20 consecutive patients
Outcome
Feasibility (number and histological quality of retrieved tissue fragments on pre-defined histometric parameters) and safety
Methodological detailssingle-group, consecutive patients
  • Single-group
  • Consecutive patients

Main finding

As reported in the abstract

Feasibility: number and histological quality of retrieved tissue fragments

Median number of fragments (≥ 1 mm diameter) per procedure processed for histopathology

17

range 9–24

Gradable tissue (visible lining layer and ≥ 4 fragments with IST)

19/20 biopsies

95%

All pre-defined histometric parameters applicable and successfully measured in gradable biopsies

19 of 19

Safety

Infectious complications · 1 month

No patients showed infectious complications
  • Procedure generally well tolerated

Original publication

The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis. Arthritis Res Ther. Published 8 July 2023. doi:10.1186/s13075-023-03101-y

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