The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis
Authors' conclusion
The access route through the anatomical snuff box in US-guided synovial biopsies of the RC joint allows for a safe and targeted collection of adequate tissue samples.
Study context
- Population
- Consecutive patients with active chronic arthritis of the wrist
- Participants
- 20 consecutive patients
- Outcome
- Feasibility (number and histological quality of retrieved tissue fragments on pre-defined histometric parameters) and safety
Methodological detailssingle-group, consecutive patients
- Single-group
- Consecutive patients
Main finding
As reported in the abstract
Feasibility: number and histological quality of retrieved tissue fragments
Median number of fragments (≥ 1 mm diameter) per procedure processed for histopathology
17
range 9–24
Gradable tissue (visible lining layer and ≥ 4 fragments with IST)
19/20 biopsies
95%
All pre-defined histometric parameters applicable and successfully measured in gradable biopsies
19 of 19
Safety
Infectious complications · 1 month
- No patients showed infectious complications
- Procedure generally well tolerated
Original publication
The access route through the anatomical snuffbox in ultrasound-guided synovial biopsy of the wrist allows for a safe and effective collection of tissue samples in inflammatory arthritis. Arthritis Res Ther. Published 8 July 2023. doi:10. 1186/ s13075-023-03101-y
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