Fibromyalgia & musculoskeletal pain

Intense symptoms of pain are associated with poor sleep, fibromyalgia, depression and sleep apnea in patients with rheumatoid arthritis and psoriatic arthritis. A register-based study

Joint Bone SpinePublished Cross-sectional study

Main finding · Pain, independent association with sleep status (regression, adjusted for age and sex)Result — go to the resultB 23 95% CI 19–26

Authors' conclusion

"Poor" sleep quality and comorbidities are independently associated with pain.

Study context

Population
Patients with Rheumatoid Arthritis (RA) and Psoriatic Arthritis (PsA) in The Finnish Rheumatology Quality Register, 1.2021–9.20226,052 RA and 1861 PsA with sleep status
Exposure
Poor vs good self-reported sleep
Outcome
Pain (PRO) and its independent associations with sleep status, comorbidities and disease activity
Methodological detailsregister-based, nation-wide, regression adjusted for age and sex
  • Register-based
  • Nation-wide
  • Regression adjusted for age and sex

Main finding

As reported in the abstract

Pain, independent association with sleep status (regression, adjusted for age and sex)

B

23

95% CI 19–26

Observational data: associations, not effects.

Further findings

Sleep status distribution · RA counts in events/value

PsA Good sleep 1460 (78%) · Poor sleep 401 (22%)

Patient-reported outcomes (PROs) in patients with no swollen joints
P < 0.001
  • PROs in patients with no swollen joints: median PROs approximately three times higher with poor sleep, both diagnoses

Objective disease activity

Median values low and similar in poor and good sleep in both diseases

Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.

Original publication

Intense symptoms of pain are associated with poor sleep, fibromyalgia, depression and sleep apnea in patients with rheumatoid arthritis and psoriatic arthritis. A register-based study. Joint Bone Spine. Published 23 May 2024. doi:10.1016/j.jbspin.2024.105744

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