Spondyloarthritis & psoriatic arthritis
Instrument selection for the ASAS core outcome set for axial spondyloarthritis
Methodological detailssystematic literature review, OMERACT filter 2.2, international working group, ASAS voting and endorsement
- Systematic literature review
- OMERACT filter 2.2
- International working group
- ASAS voting and endorsement
Recommendations
As issued by the authors
7 instruments mandatory for all trials: ASDAS, Numerical Rate Scale (NRS) PGA of disease activity, NRS total back pain, average NRS of duration and severity of morning stiffness, NRS fatigue, BASFI and ASAS Health Index
9 additional instruments mandatory for DMARD trials: MRI activity Spondyloarthritis Research Consortium of Canada (SPARCC) sacroiliac joints and SPARCC spine, uveitis, IBD and psoriasis assessed as recommended by ASAS, 44 swollen joint count, MASES, dactylitis count and mSASSS
Imaging outcomes mandatory in at least one trial for a drug tested for DMARD properties
11 additional instruments endorsed by ASAS, usable in axial spondyloarthritis (axSpA) trials on top of the core instruments
Original publication
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