Pediatric rheumatology

Influenza vaccine uptake in juvenile idiopathic arthritis during the COVID-19 pandemic: a multi-centre cross-sectional study by PRES vaccination working party

Pediatr Rheumatol Online JPublished Cross-sectional study

Authors' conclusion

Families of children with JIA reported an increasing flu vaccine uptake and a high intention for COVID-19 vaccine administration. Previous vaccination behavior was shown as a significant predictor of future behaviour.

Study context

Population
Children with Juvenile Idiopathic Arthritis (JIA), via their caregivers, across 9 countries
Participants
655 JIA caregivers
Exposure
2020-2021 season vs 2019-2020 season
Outcome
Influenza vaccination rate
Follow-up
2020-2021 season
Methodological detailsmulti-centre, 9 countries, anonymous caregiver questionnaire
  • Multi-centre
  • 9 countries
  • Anonymous caregiver questionnaire

Main finding

As reported in the abstract

Influenza vaccination

P < 0.01

Observational data: associations, not effects.

Further findings

OutcomeValuesP value
Flu vaccination by caregiver employmentEmployed/self-employed vs UnemployedEmployed 28.2% · Self-employed 29.9% · Unemployed 13.9%P < 0.01
Flu vaccination by caregiver educationTertiary education vs Elementary educationTertiary education 28% · Elementary education 9.7%P < 0.01
Inclination towards SARS-CoV-2 vaccination among caregivers who previously vaccinated for influenza — Inclination towards SARS-CoV-2 vaccination (as printed) · greater inclination
73.4% and 79.5% · P < 0.01

Caregiver concerns and COVID-19 vaccination support

Concern about child's vulnerability to SARS-CoV-2 due to JIA
51.3%
Concern about severe COVID-19 disease due to JIA
85.3%
Supporting COVID-19 vaccination
51.3%

Original publication

Influenza vaccine uptake in juvenile idiopathic arthritis during the COVID-19 pandemic: a multi-centre cross-sectional study by PRES vaccination working party. Pediatr Rheumatol Online J. Published 15 October 2025. doi:10.1186/s12969-025-01158-4

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