Influenza vaccine uptake in juvenile idiopathic arthritis during the COVID-19 pandemic: a multi-centre cross-sectional study by PRES vaccination working party
Authors' conclusion
Families of children with JIA reported an increasing flu vaccine uptake and a high intention for COVID-19 vaccine administration. Previous vaccination behavior was shown as a significant predictor of future behaviour.
Study context
- Population
- Children with Juvenile Idiopathic Arthritis (JIA), via their caregivers, across 9 countries
- Participants
- 655 JIA caregivers
- Exposure
- 2020-2021 season vs 2019-2020 season
- Outcome
- Influenza vaccination rate
- Follow-up
- 2020-2021 season
Methodological detailsmulti-centre, 9 countries, anonymous caregiver questionnaire
- Multi-centre
- 9 countries
- Anonymous caregiver questionnaire
Main finding
As reported in the abstract
Influenza vaccination
P < 0.01
Observational data: associations, not effects.
Further findings
| Outcome | Values | P value |
|---|---|---|
| Flu vaccination by caregiver employmentEmployed/self-employed vs Unemployed | Employed 28.2% · Self-employed 29.9% · Unemployed 13.9% | P < 0.01 |
| Flu vaccination by caregiver educationTertiary education vs Elementary education | Tertiary education 28% · Elementary education 9.7% | P < 0.01 |
- Inclination towards SARS-CoV-2 vaccination among caregivers who previously vaccinated for influenza — Inclination towards SARS-CoV-2 vaccination (as printed) · greater inclination
- 73.4% and 79.5% · P < 0.01
Caregiver concerns and COVID-19 vaccination support
- Concern about child's vulnerability to SARS-CoV-2 due to JIA
- 51.3%
- Concern about severe COVID-19 disease due to JIA
- 85.3%
- Supporting COVID-19 vaccination
- 51.3%
Original publication
Influenza vaccine uptake in juvenile idiopathic arthritis during the COVID-19 pandemic: a multi-centre cross-sectional study by PRES vaccination working party. Pediatr Rheumatol Online J. Published 15 October 2025. doi:10. 1186/ s12969-025-01158-4
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