Influence of Social Support, Financial Status, and Lifestyle on the Disparity Between Inflammation and Disability in Rheumatoid Arthritis
Authors' conclusion
these factors might influence disability over the following decade.
Study context
- Population
- People with rheumatoid arthritis (RA) in the ESPOIR cohort (mean age ± SD 48.3 ± 12.2 years; 79.2% women)37.2% excess disability
- Participants
- 538 people
- Exposure
- Contextual factors and excess disability group membership
- Excess disabilityn = 200
- Outcome
- Excess disability group membership
- Follow-up
- 10 years
Methodological detailsanalysis of the ESPOIR cohort, structural equation models, validation in 2 independent data sets (NOAR, ERAN)
- Analysis of the ESPOIR cohort
- Structural equation models
- Validation in 2 independent data sets (NOAR, ERAN)
Main finding
As reported in the abstract
Association with excess disability group membership
Excess disability
37.2%
200
- Less social support, β
- 0.17 (95% CI 0.08, 0.26)
- Worse financial situation, β
- 0.24 (95% CI 0.14, 0.34)
- Less exercise, β
- 0.17 (95% CI 0.09-0.25)
- Less education, β
- 0.15 (95% CI 0.06, 0.23)
Observational data: associations, not effects.
Further findings
Mediation by patient-reported outcomes
- Fatigue and depression mediated a small proportion of these effects
Validation in NOAR and ERAN
- Similar results in NOAR and ERAN
Original publication
Influence of Social Support, Financial Status, and Lifestyle on the Disparity Between Inflammation and Disability in Rheumatoid Arthritis. Arthritis Care Res (Hoboken). Published 28 December 2022. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →