Lupus & antiphospholipid syndrome

Indicators of Functional Disability by Receipt of Disability Benefits Among Individuals With Systemic Lupus Erythematosus

J RheumatolPublished Cross-sectional study

Authors' conclusion

Receipt of disability benefits may be an incomplete marker of functioning.

Study context

Population
Individuals with systemic lupus erythematosus (SLE) from a population-based SLE cohort (mean age 46.2 years, 91.7% women, 82.6% Black)
Participants
443 individuals
Exposure
Receipt vs no receipt of disability benefits
Outcome
Prevalence of potential functional disability indicators (functioning impairments, activity limitations, participation restrictions)
Methodological detailspopulation-based SLE cohort, multivariable logistic regression, adjusted prevalence estimates (postestimation margins)
  • Population-based SLE cohort
  • Multivariable logistic regression
  • Adjusted prevalence estimates (postestimation margins)

Main finding

As reported in the abstract

Impaired physical performance (SPPB score ≤ 10)

P < 0.001

Observational data: associations, not effects.

Further findings

Impaired fluid cognition (NIH Toolbox composite < 77.5)

P = 0.01

Self-reported physical limitations (T-score < 35)

P < 0.001

Difficulty with ≥ 1 IADL

P < 0.001

Difficulty with ≥ 1 BADL

P < 0.001

Work restriction (any effect of health on ability to work)

P = 0.09

Restricted community mobility

P < 0.001

Original publication

Indicators of Functional Disability by Receipt of Disability Benefits Among Individuals With Systemic Lupus Erythematosus. J Rheumatol. Published 15 March 2025. doi:10.3899/jrheum.2024-0961

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