Spondyloarthritis & psoriatic arthritis
Increased vascular inflammation on PET/CT in psoriatic arthritis patients in comparison with controls
Authors' conclusion
Aortic vascular inflammation was significantly increased in patients with active PsA compared with controls.
Study context
- Population
- Patients with active PsA and controls with melanoma
- Participants
- 75 vs 40
- Exposure
- PsA vs controls with melanoma
- PsAn = 75
- Controlsn = 40reference
- Outcome
- Aortic vascular inflammation on 18-fluorodeoxyglucose PET/CT (target-to-background ratio)
Methodological detailsPsA patients from an ongoing clinical trial, retrospective control group
- PsA patients from an ongoing clinical trial
- Retrospective control group
Main finding
As reported in the abstract
Mean target-to-background ratio, entire aorta
PsA
1.63
mean · ± 0.17
Controls
1.49
mean · ± 0.16
P = <0.001
Observational data: associations, not effects.
Further findings
Association of vascular inflammation with disease-related parameters in PsA
- Vascular inflammation was not associated with disease-related parameters
Original publication
Increased vascular inflammation on PET/CT in psoriatic arthritis patients in comparison with controls. RMD Open. Published 30 January 2024. doi:10.
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