Sjögren's disease & overlap diseases

Increased prevalence of hearing loss, tinnitus and sudden deafness among patients with Sjögren’s syndrome

RMD OpenPublished Retrospective cohort study

Authors' conclusion

We found higher prevalence of hearing loss, vertigo, tinnitus and sudden deafness among patients with Sjögren's syndrome relative to comparison patients.

Study context

Population
Patients with Sjögren's syndrome and matched comparison patients, Taiwan Longitudinal Health Insurance Database and registered catastrophic illness datasetpropensity score-matched
Participants
20,266 vs 60,798
Exposure
SjD vs propensity score-matched comparison patients
  • Sjögren's syndromen = 20,266
  • Comparisonn = 60,798reference
Outcome
Prevalence of tinnitus, hearing loss, vertigo and sudden deafness
Methodological detailspropensity score-matched, multivariable logistic regression
  • Propensity score-matched
  • Multivariable logistic regression

Main finding

As reported in the abstract

Each group vs comparisonEstimate (95% CI)
SjD
aOR (tinnitus) 1.690(1.596–1.788)
SjD
aOR (sudden deafness) 1.368(1.137–1.647)
SjD
aOR (hearing loss) 1.724(1.598–1.859)
SjD
aOR (vertigo) 1.473(1.360–1.597)

Observational data: associations, not effects.

Further findings

OutcomeComparisonP value
Prevalence of tinnitusSjD vs Comparison · χ2 test6.3%P < 0.001
Prevalence of hearing lossSjD vs Comparison · χ2 test3.3%P < 0.001
Prevalence of vertigoSjD vs Comparison · χ2 test3.2%P < 0.001
Prevalence of sudden deafnessSjD vs Comparison · χ2 test0.6%P < 0.001
  • Prevalence of tinnitus: SjD 10.1%
  • Prevalence of hearing loss: SjD 5.6%
  • Prevalence of vertigo: SjD 4.6%
  • Prevalence of sudden deafness: SjD 0.8%

Original publication

Increased prevalence of hearing loss, tinnitus and sudden deafness among patients with Sjögren’s syndrome. RMD Open. Published 19 January 2024. doi:10.1136/rmdopen-2023-003308

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