Spondyloarthritis & psoriatic arthritis
Incidence rate and risk factors of arrhythmias in patients with psoriatic arthritis
Authors' conclusion
Higher PsA disease activity is associated with higher atrial tachyarrhythmia risk.
Study context
- Population
- Patients with PsA followed prospectively from 1994 to 2024, evaluated at 6-to-12-month intervals
- Participants
- 1,670 patients
- Exposure
- Measures of PsA disease activity and arrhythmia risk
- Outcome
- Incidence and risk factors of arrhythmias: atrial tachyarrhythmia, ventricular tachyarrhythmia and bradycardia/pacemaker
Methodological detailsCox proportional hazards models, adjusted for sex, PsA duration, cardiovascular risk factors and medications
- Cox proportional hazards models
- Adjusted for sex, PsA duration, cardiovascular risk factors and medications
Main finding
As reported in the abstract
Cumulative incidence rate of arrhythmias · By age 70
Atrial tachyarrhythmia cumulative incidence rate (CIR) (80 events)
7.82%
Ventricular tachyarrhythmia CIR (11 events)
0.67%
Bradycardia/pacemaker CIR (17 events)
0.45%
Observational data: associations, not effects.
Further findings
| Outcome | Estimate | |
|---|---|---|
| Atrial tachyarrhythmia: remission/low vs high disease activity state (multivariable)Remission/low disease activityvs High disease activity | current HR 0.49 (95% CI 0.26–0.92) | |
| Atrial tachyarrhythmia: remission/low vs high disease activity state (multivariable)Remission/low disease activityvs High disease activity | adjusted mean HR 0.46 (95% CI 0.23–0.91) | |
| 0.20.5125Ratio (log scale) |
Atrial tachyarrhythmia: higher three-item VAS (3-VAS) (multivariable)
| Estimate | ||
|---|---|---|
| Higher 3-VAS | current level HR 1.18 (95% CI 1.04–1.33) | |
| Higher 3-VAS | adjusted mean HR 1.22 (95% CI 1.04–1.44) | |
| 0.512Ratio (log scale) |
Original publication
Incidence rate and risk factors of arrhythmias in patients with psoriatic arthritis. RMD Open. Published 22 January 2026. doi:10.
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