Pediatric rheumatology

Incidence of Orofacial Manifestations of Juvenile Idiopathic Arthritis From Diagnosis to Adult Care Transition: A Population‐Based Cohort Study

Arthritis RheumatolPublished Population-based cohort study

Authors' conclusion

Orofacial signs and symptoms were frequent findings in children and adolescents with JIA. TMJ involvement was seen in 30.1% of the cohort; and 20.6% of the total cohort developed JIA-related dentofacial deformity before transition into adult care.

Study context

Population
Patients with juvenile idiopathic arthritis (JIA) referred for routine orofacial examinations, Regional Specialist Craniofacial Clinic of Western Denmark, 2000–2018mean temporomandibular joint (TMJ) observation 4.0 years
Participants
613 patients
Outcome
Cumulative incidence of orofacial conditions related to TMJ JIA
Follow-up
From JIA onset to transition into adult care
Methodological detailslongitudinal
  • Longitudinal

Main finding

As reported in the abstract

Cumulative incidence of JIA involvement of the TMJ

TMJ involvement

30.1%

Observational data: associations, not effects.

Further findings

Arthritis-induced dentofacial deformity

Dentofacial deformity
20.6%

Several events with orofacial symptoms and dentofacial dysfunction

Orofacial symptoms
23.5%
Dentofacial dysfunction
52%

Features associated with TMJ involvement

Young age at diagnosis (<9 years), female gender and ANA positivity significantly associated with TMJ involvement

Original publication

Incidence of Orofacial Manifestations of Juvenile Idiopathic Arthritis From Diagnosis to Adult Care Transition: A Population‐Based Cohort Study. Arthritis Rheumatol. Published 6 June 2023. doi:10.1002/art.42481

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