Differences between leukemic arthritis and juvenile idiopathic arthritis
Study context
- Population
- Patients <16 years, both genders, first presenting to pediatric rheumatology with probable juvenile idiopathic arthritis (JIA), arthritis and no peripheral blood blastsanalysed
- Participants
- 76 patients
- Exposure
- Leukemic arthritis vs JIA at disease onset
- Leukemic arthritis (LA)n = 14
- JIAn = 62reference
- Outcome
- Clinical and laboratory differences between LA and JIA at disease onset
- Follow-up
- Onset of the disease
Methodological detailsbinary logistic regression model
- Binary logistic regression model
Main finding
As reported in the abstract
onset
- Mean age at diagnosis lower in LA
- Female gender prevailed in JIA
- Time to onset of symptoms lower in LA
- LA: increased pain intensity, fever, weight loss, nocturnal diaphoresis, lymph node enlargement, hepatosplenomegaly, and pain not improving with analgesics
- Significant laboratory parameters: anemia, leukopenia, neutropenia
- Platelet count significant but in a low normal value vs JIA
Observational data: associations, not effects.
Further findings
Binary logistic regression model to differentiate LA from JIA
- Probability associated with the statistic (Chi-square)
- 0.000
- Cox and Snell R2
- 0.615
- Nagelkerke R2
- 1
- Cases correctly classified
- 100%
Original publication
Differences between leukemic arthritis and juvenile idiopathic arthritis. Pediatr Rheumatol Online J. Published 31 May 2023. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →