Incidence of seropositive and seronegative rheumatoid arthritis in Denmark: a nationwide population-based study
Authors' conclusion
The IR of seropositive RA increased over time, whereas the IR of seronegative RA decreased.
Study context
- Population
- General population of Denmark, Danish healthcare and clinical quality registries, 2000–2018
- Exposure
- Seropositive rheumatoid arthritis (RA) vs seronegative RA
- Outcome
- Trends in annual age- and sex-standardized IRs of seropositive and seronegative RA
Methodological detailsregistry-based, prespecified seropositivity definitions, age- and sex-standardized incidence rates
- Registry-based
- Prespecified seropositivity definitions
- Age- and sex-standardized incidence rates
Main finding
As reported in the abstract
Age- and sex-standardized IR (combined laboratory, physician-reported autoantibody and ICD-10 definition) · 2018
Observational data: associations, not effects.
Further findings
Level of antibody testing
- Increased significantly during the study period
Original publication
Incidence of seropositive and seronegative rheumatoid arthritis in Denmark: a nationwide population-based study. Scand J Rheumatol. Published 8 July 2024. doi:10. 1080/ 03009742. 2024. 2365540
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