Rheumatoid arthritis

Incidence of seropositive and seronegative rheumatoid arthritis in Denmark: a nationwide population-based study

Scand J RheumatolPublished Nationwide population-based cohort study

Authors' conclusion

The IR of seropositive RA increased over time, whereas the IR of seronegative RA decreased.

Study context

Population
General population of Denmark, Danish healthcare and clinical quality registries, 2000–2018
Exposure
Seropositive rheumatoid arthritis (RA) vs seronegative RA
Outcome
Trends in annual age- and sex-standardized IRs of seropositive and seronegative RA
Methodological detailsregistry-based, prespecified seropositivity definitions, age- and sex-standardized incidence rates
  • Registry-based
  • Prespecified seropositivity definitions
  • Age- and sex-standardized incidence rates

Main finding

As reported in the abstract

Age- and sex-standardized IR (combined laboratory, physician-reported autoantibody and ICD-10 definition) · 2018

Observational data: associations, not effects.

Further findings

Level of antibody testing

Increased significantly during the study period

Original publication

Incidence of seropositive and seronegative rheumatoid arthritis in Denmark: a nationwide population-based study. Scand J Rheumatol. Published 8 July 2024. doi:10.1080/03009742.2024.2365540

Composed by AI from the published abstract and checked against it. How Briefs are made →

Get them every week

New studies on this topic in My Week and in your Monday e-mail.

We e-mail you a sign-in link and a code. No password, no spam.