Incidence of hip fractures in persons with and without Parkinson’s disease in Finland: a 15-year longitudinal study
Main finding · Incident hip fractureResult — go to the resultHazard ratio 1.82 95% CI 1.47–2.26Authors' conclusion
As the risk of hip fracture is elevated already years before the diagnosis of PD, it is important to manage fall risks concomitantly while applying the diagnostic procedures for PD.
Study context
- Population
- Persons diagnosed with Parkinson's disease (PD) 2000–2009 in Finland and 1:2 matched persons without PD; follow-up from 5 years before to 10 years after PD diagnosis
- Participants
- 33,153 eligible persons
- Exposure
- Persons with PD vs matched persons without PD
- Outcome
- Incident hip fracture
- Follow-up
- 5 years before to 10 years after PD diagnosis
Methodological details1:2 matched comparison cohort, nationwide (Finland)
- 1:2 matched comparison cohort
- Nationwide (Finland)
Main finding
As reported in the abstract
Hazard ratio
1.82
95% CI 1.47–2.26
By group
With PDvs Without PD
HR 1.82 (95% CI 1.47–2.26)
Observational data: associations, not effects.
Further findings
Annual incidence rate of hip fracture · 3 years before diagnosis
Annual incidence rate of hip fracture · up to 10 years after diagnosis
- Annual incidence rate of hip fracture: higher annual incidence rates in PD starting from 3 years before diagnosis
Medications at hip fracture
- Prevalence of fall-risk-increasing medications but not anti-osteoporosis medications was higher at hip fractures in PD than without PD
Original publication
Incidence of hip fractures in persons with and without Parkinson’s disease in Finland: a 15-year longitudinal study. Osteoporos Int. Published 29 July 2025. doi:10.
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