Incidence of chronic recurrent multifocal osteomyelitis in children and adolescents in the United Kingdom (UK) and Republic of Ireland
Authors' conclusion
This study estimates an average annual CRMO incidence of 0.65 cases per 100 000 children and adolescents in the UK and ROI.
Study context
- Population
- Children and young people under 16 years newly diagnosed with chronic recurrent multifocal osteomyelitis (CRMO) in the UK and Republic of Ireland, October 2020 to November 2022165 confirmed, 20 probable analysed
- Participants
- 288 children
- Outcome
- Incidence of CRMO
Methodological detailsmonthly surveys of all paediatric consultants and paediatric orthopaedic surgeons, standardized questionnaire, 288 patients reported over the surveillance period
- Monthly surveys of all paediatric consultants and paediatric orthopaedic surgeons
- Standardized questionnaire
- 288 patients reported over the surveillance period
Main finding
As reported in the abstract
Average annual CRMO incidence
Average annual incidence, cases per 100 000 children and adolescents
0.65
Observational data: associations, not effects.
Further findings
Clinical presentation
- Male patients more likely to present with multifocal disease
- Negative correlation between reporting clavicular and leg pain
Investigations
- Whole-body MRI
- 80.0%
- Bone biopsies
- 51.1%
Initial treatments
- NSAIDs
- 93.9%
- Bisphosphonates
- 44.8%
Original publication
Incidence of chronic recurrent multifocal osteomyelitis in children and adolescents in the UK and Republic of Ireland. Rheumatology (Oxford). Published 21 August 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →