Spondyloarthritis & psoriatic arthritis
Impact Profiles in Psoriatic Arthritis: An Exploratory Latent Class Analysis of the Assessment of SpondyloArthritis International Society Health Index
Authors' conclusion
LCA of the ASAS HI identified 6 clinically meaningful health impact profiles in PsA.
Study context
- Population
- Patients with PsA, profiled by responses to 17 dichotomous ASAS HI items
- Participants
- 90 patients
- Outcome
- Distinct subgroups (latent classes) of patients with PsA based on ASAS HI responses
Methodological detailsexploratory latent class analysis, sensitivity analyses with 3 to 4 classes
- Exploratory latent class analysis
- Sensitivity analyses with 3 to 4 classes
Main finding
As reported in the abstract
Latent class solution of ASAS HI
Mean ASAS HI, class 0
1.2
Mean ASAS HI, class 5
11.6
Average posterior probabilities (AvePP), all classes
> 0.86
Observational data: associations, not effects.
Further findings
Sensitivity analyses (K = 3 and K = 4)
- Reproduced the same gradient of impact but less granular separation
Original publication
Impact Profiles in Psoriatic Arthritis: An Exploratory Latent Class Analysis of the Assessment of SpondyloArthritis International Society Health Index. J Rheumatol. Published 1 December 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →