Lupus & antiphospholipid syndrome

Impact of parenting on patient-reported outcomes in female patients with systemic lupus erythematosus: A cross-sectional study of the LUNA registry

LupusPublished Cross-sectional study

Main finding · LupusPRO QoL scoresResult — go to the resultRegression coefficient 12.16 95% CI 0.97–23.35

Authors' conclusion

Parenting of young children did not worsen QoL in patients with SLE; rather, it was associated with better cognitive function.

Study context

Population
Female patients with systemic lupus erythematosus (SLE), Lupus Registry of Nationwide Institutions (median age 44 years; median disease duration 12 years)
Participants
630 patients
Exposure
Parenting vs no children
  • Young childrenn = 71
  • School-aged children onlyn = 50
  • Without childrenn = 509reference
Outcome
Quality of life (QoL) measured using the LupusPRO scale
Methodological detailsregistry-based (LUNA), multiple regression analysis
  • Registry-based (LUNA)
  • Multiple regression analysis

Main finding

LupusPRO QoL scores

Regression coefficient

12.16

95% CI 0.97–23.35

P = 0.033

As reported in the abstract

Observational data: associations, not effects.

Original publication

Impact of parenting on patient-reported outcomes in female patients with systemic lupus erythematosus: A cross-sectional study of the LUNA registry. Lupus. Published 30 July 2026. doi:10.1177/09612033261474991

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