Lupus & antiphospholipid syndrome
Identification of common MicroRNAs expression signatures in antiphospholipid syndrome and thromboembolic disease: A scoping review
Authors' conclusion
We observed that APS shares a common miRNAs signature with non-APS related thrombosis, suggesting that miRNA expression profiles may serve as markers of thrombotic risk in APS.
Study context
- Population
- Studies of miRNA profiles in antiphospholipid syndrome (APS) and other thromboembolic diseases45 studies
- Outcome
- Shared miRNA profiles associated with APS and other thromboembolic diseases
Methodological details45 relevant studies identified out of 1020 references
- 45 relevant studies identified out of 1020 references
Main finding
As reported in the abstract
miRNAs shared by APS and thrombosis
- Associated with APS and arterial thrombosis: miRs-124-3p, 125b-5p, 125a-5p, and 17-5p
- Associated with APS and venous thrombosis: miRs-106a-5p, 146b-5p, 15a-5p, 222-3p, and 451a
- Associated with APS and both arterial and venous thrombosis: miR-126a-3p
Original publication
Identification of common MicroRNAs expression signatures in antiphospholipid syndrome and thromboembolic disease: A scoping review. Lupus. Published 27 September 2024. doi:10.
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