Lupus & antiphospholipid syndrome

Human papillomavirus vaccine uptake in ethnically diverse women living with systemic lupus erythematosus

LupusPublished Cross-sectional study

Authors' conclusion

We found low HPV vaccine uptake among racial and ethnically diverse women with SLE. Older age, Spanish language, increased perceived barriers, and increased cues to action were significantly correlated with HPV vaccination.

Study context

Population
Ethnically diverse women with systemic lupus erythematosus (SLE) aged 21–45, for whom the human papillomavirus (HPV) vaccine is recommended by the US Food and Drug Administration (FDA)median age 33 (IQR 27–40)
Participants
75 women
Outcome
Self-reported HPV vaccination as recommended by Advisory Committee on Immunization Practices (ACIP)

Main finding

As reported in the abstract

Self-reported HPV vaccination (as recommended by ACIP)

Women with SLE who had received HPV vaccination

20

27%

Observational data: associations, not effects.

Further findings

Factors associated with HPV vaccination

Increased 'perceived barriers' (Health Belief Model (HBM)) associated with no vaccination, r
−0.41, p < 0.01
Increased 'cues to action' (HBM) associated with increased vaccination, r
0.30, p < 0.01
Age, multivariable-adjusted OR for HPV vaccination
0.82 (95% CI 0.73-0.93)
Older women and Spanish-speaking patients less likely to have received HPV vaccine
  • After multivariable adjustment of significant covariates

Original publication

Human papillomavirus vaccine uptake in ethnically diverse women living with systemic lupus erythematosus. Lupus. Published 25 October 2025. doi:10.1177/09612033251390599

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