Lupus & antiphospholipid syndrome
Health seeking behaviour and diagnostic delays in systemic lupus erythematosus (SLE): A multi-ethnic Malaysian cohort study
Main finding · Delayed diagnosisResult — go to the resultOdds ratio 0.30 CI 0.09–0.93Authors' conclusion
There were ethnic disparities in the early diagnosis of SLE in Malaysia, with Indian patients having a longer interval between the first symptom and diagnosis while the Chinese were associated with lower diagnostic delays.
Study context
- Population
- SLE patients who visited the institute between January 2020 and June 2021, Malaysia
- Participants
- 154 patients
- Exposure
- Delayed diagnosis vs no delay; by ethnicity
- Outcome
- Diagnostic delay (interval between initial symptoms and SLE diagnosis of more than 6 months) and associated factors
Methodological detailsmulti-ethnic cohort, univariate and multivariate logistic regression
- Multi-ethnic cohort
- Univariate and multivariate logistic regression
Main finding
Delayed diagnosis
Odds ratio
0.30
CI 0.09–0.93
P = 0.037
By group
Chinese
OR 0.30 (CI 0.09–0.93); P = 0.037
As reported in the abstract
- Overall delayed diagnosis
- 24% (n = 37)
- Ethnic difference in delay (Indian vs Malay vs Chinese)
- P = 0.037
Observational data: associations, not effects.
Further findings
LLDAS at 12 months, delayed vs no delayed diagnosis
P = 0.006
Delayed diagnosis by rash (with vs without)
- Delayed diagnosis with rash vs without
- 37.8% vs 22.2%, p = 0.08
Delayed diagnosis by frothy urine (with vs without)
- Delayed diagnosis with frothy urine vs without
- 8.1% vs 21.4%, p = 0.09
Original publication
Health seeking behaviour and diagnostic delays in SLE: A multi-ethnic Malaysian cohort study. Lupus. Published 7 November 2024. doi:10.
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