Growth arrest-specific protein 6 as a marker of nephritis in systemic sclerosis and juvenile systemic lupus erythematosus patients
Performance · Prediction of nephritis (proteinuria) in SSc by serum GAS6Result — go to the resultOdds ratio 1.06 95% CI 1.0–1.1Authors' conclusion
GAS6 is an independent predictor of nephritis in patients with SSc. However, there is no association between GAS6 and nephritis in juvenile patients with SLE.
Study context
- Population
- Adults with systemic sclerosis (SSc) and children with systemic lupus Erythematosus (SLE)
- Participants
- 60 vs 40
- Comparison
- Serum GAS6 in patients with vs without nephritis
- SScn = 60
- SLEn = 40
- Outcome
- Serum GAS6 (ELISA) as a predictor of renal impairment
Performance
As reported in the abstract
Prediction of nephritis (proteinuria) in SSc by serum GAS6
Odds ratio
1.06
95% CI 1.0–1.1
By group
GAS6
12.2
cutoff · ng/mL
GAS6
OR 1.06 (95% CI 1.0–1.1)
Original publication
Growth arrest-specific protein 6 as a marker of nephritis in systemic sclerosis and juvenile systemic lupus erythematosus patients. Lupus. Published 29 May 2024. doi:10.
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