Spondyloarthritis & psoriatic arthritis
Group for Research and Assessment of Psoriasis and Psoriatic Arthritis (GRAPPA) Debate: Be it Resolved That Clinical Enthesitis Indices Do Not Reflect True Enthesitis and Hence Should Be Discontinued
Study context
- Population
- Psoriatic disease (PsD)
- Comparison
- Discontinuation vs continued use of traditional clinical enthesitis indices in PsD
Methodological detailsGRAPPA 2024 annual meeting
- GRAPPA 2024 annual meeting
Main finding
As reported in the abstract
- For discontinuation (Aydin): clinical indices often capture "enthesalgia" rather than true inflammatory enthesitis, may lack specificity for inflammation, and show high placebo response; prioritise emerging imaging tools
- Against discontinuation (Deodhar): indices used successfully in multiple RCTs leading to approval of numerous PsA treatments; imaging such as US has operator dependency, variability in interpretation and no regulatory approval as a standardised outcome measure
Original publication
GRAPPA Debate: Be it Resolved That Clinical Enthesitis Indices Do Not Reflect True Enthesitis and Hence Should Be Discontinued. J Rheumatol. Published 1 October 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →