Global burden of low bone mineral density related fractures in pre- and post-menopausal women from 1990 to 2021, with projections to 2050
Authors' conclusion
The global burden of LBMD-fractures remains concerning, particularly among post-menopausal women.
Study context
- Population
- Women globally, by menopausal status, 1990–2021
- Exposure
- Pre-menopausal vs post-menopausal women
- Outcome
- Counts and age-standardized rates of deaths and DALYs caused by low BMD-related fractures
- Follow-up
- 2021
Methodological detailsestimated annual percent changes, health inequality and decomposition analyses, Bayesian age-period-cohort projection to 2050
- Estimated annual percent changes
- Health inequality and decomposition analyses
- Bayesian age-period-cohort projection to 2050
Main finding
As reported in the abstract
| Group | Value | DALYs |
|---|---|---|
| Pre-menopausal women | 1,358 (95% UI 983–1,602) deaths | 298,253 (95% UI: 220,588 to 397,894) |
| Post-menopausal women | 189,025 (95% UI 136,288–227,914) deaths | 6,735,144 (95% UI: 5,253,930 to 8,436,635) |
Value
Pre-menopausal women1,358 (95% UI 983–1,602) deaths
Post-menopausal women189,025 (95% UI 136,288–227,914) deaths
DALYs
Pre-menopausal women298,253 (95% UI: 220,588 to 397,894)
Post-menopausal women6,735,144 (95% UI: 5,253,930 to 8,436,635)
Observational data: associations, not effects.
Further findings
- Projected deaths and DALYs, post-menopausal women · 2050
- 397,537 · deaths
Projected deaths and DALYs, post-menopausal women · 2050
- No obvious changes in age-standardized rates (ASRs) across 2022 to 2050
Geographic distribution
- Burden higher in Asia, Europe and North America; relatively lower in Africa
Drivers of DALYs (decomposition)
- Population growth was the most significant factor driving DALYs
Original publication
Global burden of low bone mineral density related fractures in pre- and post-menopausal women from 1990 to 2021, with projections to 2050. Osteoporos Int. Published 23 June 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →