Generative Artificial Intelligence Utilization and Perspectives Among Reproductive‐Age Women With Systemic Autoimmune and Rheumatic Diseases

Arthritis Care Res (Hoboken)Published Cross-sectional study

Authors' conclusion

Participants expressed interest in using generative AI for health information-seeking but preferred tools endorsed by rheumatologists.

Study context

Population
Women ages 18 to 48 years with diverse systemic autoimmune and rheumatic diseases (SARDs) enrolled in a research registry190 completed
Participants
270 participants
Outcome
Use of and receptivity to generative AI for health information-seeking
Methodological detailssurvey, research registry, exploratory multivariable ordinal logistic regression, thematic analysis
  • Survey
  • Research registry
  • Exploratory multivariable ordinal logistic regression
  • Thematic analysis

Main finding

As reported in the abstract

Familiar with generative artificial intelligence (AI)
77.4%
Perceived it might benefit health care
nearly 90%
Had used it to answer health questions
29%
Willing to use a physician-recommended AI tool
88%
Interest in generative AI for information about medication safety during pregnancy or lactation
Approximately one-third

Observational data: associations, not effects.

Further findings

Interest in a hypothetical generative AI tool for SARDs management: association with desire for personalized recommendations

Desire for personalized recommendations, OR
2.89 (95% CI 1.25-6.67)

Interest in generative AI for medication safety in pregnancy or lactation: associated factors

Age (younger), OR
0.93 (95% CI 0.88-0.99)
Desire for timely access, OR
4.71 (95% CI 2.07-10.71)
Increased information access, OR
2.56 (95% CI 1.20-5.43)

Original publication

Generative Artificial Intelligence Utilization and Perspectives Among Reproductive‐Age Women With Systemic Autoimmune and Rheumatic Diseases. Arthritis Care Res (Hoboken). Published 25 September 2026. doi:10.1002/acr.80168

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