Spondyloarthritis & psoriatic arthritis
From pain catastrophising to multidimensional psychological distress: unravelling the complexity of difficult-to-treat psoriatic arthritis
Authors' conclusion
Our results indicate that D2T status remains a significant predictor of PC, even when controlling for relevant clinical characteristics, including fibromyalgia and disease activity, highlighting the intricate relationship between D2T PsA and psychological dimensions, which may exacerbate disease burden and hinder treatment targets.
Study context
- Population
- PsA patients
- Participants
- 182 patients
- Exposure
- Difficult-to-treat (D2T) vs non-D2T PsA
- Outcome
- Pain catastrophising (PC) (PCS score) and its domains (helplessness, rumination, magnification) by D2T status
Methodological detailsunivariable and multivariable regression
- Univariable and multivariable regression
Main finding
As reported in the abstract
PCS score associated with D2T (multivariable, adjusted for age, sex, disease duration, BMI, fibromyalgia and disease activity)
B
7.637
95% CI 3.261–12.014p=0.001
Observational data: associations, not effects.
Further findings
- D2T predicted higher HADS anxiety scores
- Association with HADS depression not statistically significant
Original publication
From pain catastrophising to multidimensional psychological distress: unravelling the complexity of difficult-to-treat psoriatic arthritis. Clin Exp Rheumatol. Published 18 February 2025. doi:10.
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