Frequently Encountered Artifacts in the Application of Dual‐Energy Computed Tomography to Cardiovascular Imaging for Urate Crystals in Gout: A Matched‐Control Study
Authors' conclusion
Artifacts that could be misconstrued as cardiovascular MSU deposits were commonly identified in patients with and without gout on non-EKG-gated DECT pulmonary angiograms.
Study context
- Population
- Patients with and without gout undergoing non-EKG-gated dual-energy computed tomography (DECT) pulmonary angiograms at a single academic center; majority male, mean age 67 years
- Participants
- 48 vs 48
- Exposure
- Patients with gout vs age- and sex-matched controls
- Goutn = 48
- Controlsn = 48reference
- Outcome
- Prevalence and characterization of cardiovascular DECT artifacts (vascular green colorization for monosodium urate (MSU))
Methodological detailsage- and sex-matched, single-centre, non-EKG-gated DECT pulmonary angiograms
- Age- and sex-matched
- Single-centre
- non-EKG-gated DECT pulmonary angiograms
Main finding
As reported in the abstract
Vascular green colorization
- Two independent observers attributed all areas of vascular green colorization to artifacts
Observational data: associations, not effects.
Further findings
Streak artifacts
Contrast medium mixing artifacts
DECT measurements vs subcutaneous tophi
- Some default DECT measurements of cardiovascular green colorization consistent with values reported for subcutaneous tophi; advanced DECT measurements not consistent with tophi
Original publication
Frequently Encountered Artifacts in the Application of Dual‐Energy Computed Tomography to Cardiovascular Imaging for Urate Crystals in Gout: A Matched‐Control Study. Arthritis Care Res (Hoboken). Published 18 March 2024. doi:10.
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