Frequency of remission achievement in the pre-treat-to-target decade in juvenile idiopathic arthritis
Authors' conclusion
A sizeable proportion of patients treated in the decade preceding the beginning of the "T2T era" and on continued follow-up did not achieve or maintain the state of CID over the long term.
Study context
- Population
- Juvenile idiopathic arthritis (JIA) patients followed at the study center 2007–2017, first seen within 6 months after disease onset, with ≥6-month follow-up (pre-T2T decade)
- Participants
- 394 patients
- Exposure
- Systemic vs Oligoarticular vs Polyarticular vs Other arthritis
- Outcome
- CID (2004 Wallace criteria)
- Follow-up
- 6, 12, 24 and 60 months after first observation
Methodological detailssingle-centre, chart review, cross-sectional assessment at 6, 12, 24 and 60 months
- Single-centre
- Chart review
- Cross-sectional assessment at 6, 12, 24 and 60 months
Main finding
As reported in the abstract
Overall frequency of CID
Clinical inactive disease (CID) at 6 months
25.1%
CID at 12 months
34.5%
CID at 24 months
44.6%
CID at 60 months
49.1%
Observational data: associations, not effects.
Further findings
CID by phenotype among patients still followed at study center · 60 months
| Outcome | Systemic | Oligoarticular | Polyarticular | Other arthritis |
|---|---|---|---|---|
| CID by phenotype (highest rates: systemic and oligoarticular subgroups) · 6 months | 32.1% | 29.5% | — not stated in the abstract | — not stated in the abstract |
| CID by phenotype (highest rates: systemic and oligoarticular subgroups) · 12 months | 40% | 41.1% | — not stated in the abstract | — not stated in the abstract |
— not stated in the abstract
- CID by phenotype among patients still followed at study center: 60-month evaluation available for 226 out of 394 patients (57.4%)
Original publication
Frequency of remission achievement in the pre-treat-to-target decade in juvenile idiopathic arthritis. Pediatr Rheumatol Online J. Published 23 January 2025. doi:10.
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