Fracture Risk Among Living Kidney Donors 25 Years After Donation
Main finding · Overall fracturesResult — go to the resultStandardized incidence ratio 0.89 95% CI 0.81–0.97Authors' conclusion
This survey study found a reduced rate of overall fractures but an excess of vertebral fractures among living kidney donors compared with controls after a mean follow-up of 25 years.
Study context
- Population
- Living kidney donors and eligible nondonor controls, Minnesota, surveyed December 2021 to July 20235,065 donors invited
- Participants
- 2,132 vs 2,014
- Exposure
- Living kidney donors vs matched nondonor controls from the general population
- Living kidney donorsn = 2,132
- Controlsn = 2,014reference
- Outcome
- Rates of overall and site-specific fractures, compared using standardized incidence ratios (SIRs)
Methodological detailsmatched population-based nondonor controls, 3 transplant centres, Survey conducted December 1, 2021, to July 31, 2023
- Matched population-based nondonor controls
- 3 transplant centres
- Survey conducted December 1, 2021, to July 31, 2023
Main finding
Overall fractures
Standardized incidence ratio
0.89
95% CI 0.81–0.97
Living kidney donorsvs Controls
SIR 0.89 (95% CI 0.81–0.97)
As reported in the abstract
Observational data: associations, not effects.
Further findings
| Outcome | SIR (95% CI) | |
|---|---|---|
| Vertebral fractures | 1.42 (1.05–1.83) | |
| 0.512Standardized incidence ratio (log scale) |
Time between donation or index date and survey
Original publication
Fracture Risk Among Living Kidney Donors 25 Years After Donation. JAMA Netw Open. Published 2 January 2024. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →