Vasculitis & polymyalgia rheumatica

First profiling of the national Swiss Clinical Quality Management giant cell arteritis and polymyalgia rheumatica registry

Clin Exp RheumatolPublished Registry-based cohort study

Authors' conclusion

Imaging has largely replaced histology for GCA diagnosis. Despite 75% of GCA patients receiving tocilizumab, one-third remained on glucocorticoids beyond 2 years.

Study context

Population
Patients with giant cell arteritis (GCA) or polymyalgia rheumatica (PMR) in the national Swiss Clinical Quality Management (SCQM) registry, August 2020–June 2024337 GCA, 99 PMR
Participants
436 patients
Exposure
GCA vs PMR
  • GCAn = 337
  • PMRn = 99
Outcome
Patient characteristics, diagnostic approaches and treatment patterns
Methodological detailsnational registry, descriptive
  • National registry
  • Descriptive

Main finding

As reported in the abstract

Patient characteristics, diagnostic approaches and treatment patterns

Female GCA 64% · PMR 56%

GCA: cranial symptoms at diagnosis
81%
GCA: visual symptoms at diagnosis
31%
GCA: polymyalgic symptoms at diagnosis
43%
PMR: shoulder girdle pain
95%
PMR: pelvic girdle pain
85%
PMR: neck pain
44%
GCA: US used for diagnosis (most used)
76%
GCA: PET-CT used
59%
GCA: MRI used
40%
GCA: temporal artery biopsy performed
29%
GCA: temporal artery biopsy positivity rate
66%
GCA: still on GC at 6 months
79%
GCA: still on GC at 12 months
50%
GCA: still on GC at 24 months
37%
Steroid-sparing agents prescribed
77%
Tocilizumab (most common steroid-sparing agent)
73%

Observational data: associations, not effects.

Further findings

Common comorbidities

Hypertension, GCA
51%
Hypertension, PMR
44%
Diabetes, GCA
15%
Diabetes, PMR
12%
Osteoporosis, GCA
26%
Osteoporosis, PMR
15%

Original publication

First profiling of the national Swiss Clinical Quality Management giant cell arteritis and polymyalgia rheumatica registry. Clin Exp Rheumatol. Published 22 April 2026. doi:10.55563/clinexprheumatol/yt7efd

Composed by AI from the published abstract and checked against it. How Briefs are made →

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