Systemic sclerosis & Raynaud's
Factors associated with satisfaction with social roles and activities among people with systemic sclerosis: a Scleroderma Patient-centered Intervention Network (SPIN) cohort cross-sectional study
Authors' conclusion
Mean satisfaction with social roles and activities is slightly lower in SSc than the general population and associated with multiple sociodemographic and disease factors.
Study context
- Population
- People with systemic sclerosis (SSc) in the multinational Scleroderma Patient-centered Intervention Network (SPIN) Cohort
- Participants
- 2,385 people
- Exposure
- SSc cohort vs US general population normative data
- SScn = 2,385
- Outcome
- Satisfaction with social roles and activities (PROMIS v2 domain T-score)
Methodological detailsmultinational cohort, multivariable regression
- Multinational cohort
- Multivariable regression
Main finding
As reported in the abstract
Satisfaction with social roles and activities T-score
SSc
48.1
mean · SD 9.9
US general population
50
mean · SD 10
Observational data: associations, not effects.
Further findings
Factors independently associated with satisfaction (multivariable regression coefficients)
- Years of education (per SD)
- 0.54, 95% CI 0.14 to 0.93
- Non-White race or ethnicity
- −1.13, 95% CI −2.18 to −0.08
- Living in Canada (reference USA)
- −1.33, 95% CI −2.40 to −0.26
- Living in the UK (reference USA)
- −2.49, 95% CI −3.92 to −1.06
- BMI (per SD)
- −1.08, 95% CI −1.47 to −0.69
- Gastrointestinal involvement
- −3.16, 95% CI −4.27 to −2.05
- Digital ulcers
- −1.90, 95% CI −3.05 to −0.76
- Moderate small joint contractures
- −1.62, 95% CI −2.78 to −0.45
- Severe small joint contractures
- −2.26, 95% CI −3.99 to −0.52
- ILD
- −1.11, 95% CI −1.97 to −0.25
- PAH
- −2.69, 95% CI −4.08 to −1.30
- RA
- −2.51, 95% CI −4.28 to −0.73
- Sjogren's syndrome
- −2.42, 95% CI −3.96 to −0.88
Original publication
Factors associated with satisfaction with social roles and activities among people with systemic sclerosis: a Scleroderma Patient-centered Intervention Network (SPIN) cohort cross-sectional study. RMD Open. Published 29 February 2024. doi:10.
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