Spondyloarthritis & psoriatic arthritis
Exploring the relationship between skin severity and Psoriatic Arthritis Disease Activity Score (PASDAS) in psoriatic arthritis: a cross-sectional study in the BSR-PsA and GRAPPA Composite Exercise (GRACE) cohorts
Authors' conclusion
These data suggest that psoriasis disease activity is represented in the composite PASDAS score, possibly through the global (patient and physician) VAS scores.
Study context
- Population
- Patients with PsA in the BSR-PsA register and the GRAPPA Composite Exercise (GRACE) dataset (baseline data)BSR-PsA 1126
- Exposure
- Severe vs less severe skin involvement (BSA cut-off of 10), matched for musculoskeletal disease activity
- Outcome
- Extent to which skin severity (BSA, DLQI) is reflected in PASDAS
Methodological detailspropensity-score matched
- Propensity-score matched
Main finding
As reported in the abstract
- In both BSR-PsA and GRACE, PASDAS, physician global VAS and patient global VAS scores increased with increasing skin scores
- Matched for musculoskeletal activity, BSR-PsA: significant differences in PASDAS, physician global score and Dermatology Life Quality Index (DLQI) by skin severity
- Matched for musculoskeletal activity, GRACE: significant differences in physician and patient global scores, DLQI and age by skin severity
- Propensity score matching for musculoskeletal disease activity
Observational data: associations, not effects.
Original publication
Exploring the relationship between skin severity and PASDAS in psoriatic arthritis: a cross-sectional study in the BSR-PsA and GRACE cohorts. Rheumatology (Oxford). Published 24 March 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →