Spondyloarthritis & psoriatic arthritis
Exploring difficult-to-manage axial spondyloarthritis: results from a Dutch clinical practice registry
Authors' conclusion
One in 10 patients with axSpA have D2M disease. Patient-reported outcomes contribute importantly to the classification of D2M axSpA. Current smoking and a history of psoriasis are associated characteristics.
Study context
- Population
- Patients with axSpA in the Dutch SpA-Net clinical practice registryanalysed
- Participants
- 263 patients
- Outcome
- Prevalence of D2M axSpA per ASAS definition
Methodological detailsregistry-based (SpA-Net), logistic regression
- Registry-based (SpA-Net)
- Logistic regression
Main finding
As reported in the abstract
Prevalence of D2M axSpA (ASAS definition)
D2M axSpA, primary ASAS definition
9.7%
D2M axSpA, variations A-C
3.6-8.7%
Treatment-refractory axSpA
1.7%
Observational data: associations, not effects.
Further findings
Characteristics associated with D2M axSpA
| OR (95% CI) | ||
|---|---|---|
| Current smoking | 3.1 (1.1–8.7) | |
| History of psoriasis | 2.8 (1.0–7.6) | |
| 0.10.31310Odds ratio (log scale) |
Components of the ASAS definition fulfilled
- Treatment failure
- 9.9-11.6%
- Insufficient disease control
- 79.7%
- Insufficient disease control, variation A
- 57.0%
- Insufficient disease control, variation B
- 44.6%
- Insufficient disease control, variation C
- 51.4%
- Problematic management
- 51.4-60.2%
Original publication
Exploring difficult-to-manage axial spondyloarthritis: results from a Dutch clinical practice registry. Rheumatology (Oxford). Published 28 February 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →