Lupus & antiphospholipid syndrome
EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study
Study context
- Population
- Females with SLEfemales with SLE
- Participants
- 30 females
- Planned comparison
- Remotely monitored, home-based, codesigned progressive exercise programme vs standard of care (habitual activity)
- Healthy control (HC)n = 15
- Primary endpoint
- Feasibility and acceptability measures
Methodological detailsfeasibility, remotely monitored home-based exercise, healthy control comparison at baseline only, Peripheral blood at weeks 0, 12 and 18: frequency, phenotype and metabolic profile of lymphocyte subsets, SLE activity biomarkers and self-reported fatigue, sleep quality and health-related quality of life at weeks 0, 12 and 18
- Feasibility
- Remotely monitored home-based exercise
- Healthy control comparison at baseline only
- Peripheral blood at weeks 0, 12 and 18: frequency, phenotype and metabolic profile of lymphocyte subsets
- SLE activity biomarkers and self-reported fatigue, sleep quality and health-related quality of life at weeks 0, 12 and 18
No results yet. This paper sets out the design of a trial; its results are to come.
Original publication
EXamining the feasibility of exerCisE to manage symptoms of Lupus (EXCEL): a protocol for a randomised controlled pilot study. Lupus Sci Med. Published 16 January 2025. doi:10.
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