Effect of Knee Extensor Power on Knee Pain in Adults With or at Risk for Osteoarthritis: The Multicenter Osteoarthritis Study
Authors' conclusion
Lower knee extensor power may be a risk factor for both worsening knee pain severity and the development of FKP in adults with or at risk for knee OA.
Study context
- Population
- Adults with or at risk for knee osteoarthritis (OA), Multicenter Osteoarthritis Study (MOST)
- Exposure
- Weakest vs strongest sex-specific quartile of baseline knee extensor power
- Outcome
- Worsening WOMAC pain and incident frequent knee pain (FKP; pain on most days in the past 30 days)
- Follow-up
- 2 years
Methodological detailsmulticentre, logistic regression with generalized estimating equations
- Multicentre
- Logistic regression with generalized estimating equations
Main finding
As reported in the abstract
Odds of worsening knee pain severity
1.35
95% CI 0.98–1.86; P for linear trend = 0.04
Weakest quartile
Odds of incident frequent knee pain (FKP)
1.95
95% CI 1.22–3.05; P for linear trend < 0.01
Weakest quartile
Observational data: associations, not effects.
Original publication
Effect of Knee Extensor Power on Knee Pain in Adults With or at Risk for Osteoarthritis: The Multicenter Osteoarthritis Study. J Rheumatol. Published 15 September 2025. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →