Fibromyalgia & musculoskeletal pain
Effect of fibromyalgia on demographic, biochemical, metabolic and inflammatory profiles: a single-centre retrospective study
Authors' conclusion
This study highlights fthe association f ibromyalgia with elevated inflammatory markers, altered metabolic parameters, and specific demographic characteristics.
Study context
- Population
- Individuals diagnosed with fibromyalgia (FM) (ACR 2016 criteria) and healthy controls
- Participants
- 174 vs 186
- Exposure
- FM vs healthy controls
- FMn = 174
- Controln = 186reference
- Outcome
- Differences in demographic, biochemical, metabolic and inflammatory indexes and rates between FM and healthy controls
Methodological detailsretrospective, single-centre
- Retrospective
- Single-centre
Main finding
As reported in the abstract
Demographic, biochemical, metabolic and inflammatory profiles
- No difference in alcohol consumption, marital status or diabetes mellitus
- Smoking rate higher and educational level lower in FM vs control
- No significant difference in waist-height ratio, triglyceride-glucose index, plasma atherogenic index, vitamin B12 and folate
- Control vs FM: P < 0.001
- Control vs FM: P = 0.039
- Control vs FM: P = 0.007
- Control vs FM: P < 0.001
- Control vs FM: P < 0.001
- FM vs Control: P = 0.001
- FM vs Control: P = 0.032
- FM vs Control: P = 0.003
- FM vs Control: P = 0.030
- FM vs Control: P = 0.003
- FM vs Control: P < 0.001
Observational data: associations, not effects.
Further findings
Correlations within FM
- Weak positive correlation between fibromyalgia impact questionnaire (FIQ) score and disease duration, pain degree and ESR, and pain degree and CRP
- Weak inverse relationship between Widespread Pain Index (WPI) and waist circumference
Original publication
Effect of fibromyalgia on demographic, biochemical, metabolic and inflammatory profiles: a single-centre retrospective study. Clin Exp Rheumatol. Published 1 April 2024. doi:10.
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