Spondyloarthritis & psoriatic arthritis

Early peripheral psoriatic arthritis: Baseline features of the first 186 patients in the French Nationwide APACHE Cohort

Joint Bone SpinePublished Prospective cohort study

Authors' conclusion

Patients with early peripheral PsA had moderate disease activity, a predominant oligoarticular profile, and a high prevalence of entheseal pain.

Study context

Population
Patients with early peripheral PsA (APACHE cohort, France), first included patients
Participants
186 first included patients
Outcome
Main baseline clinical characteristics
Follow-up
Baseline
Methodological detailsmulticentre, national, ongoing, descriptive baseline analysis, planned follow-up of 10 years
  • Multicentre
  • National
  • Ongoing
  • Descriptive baseline analysis
  • Planned follow-up of 10 years

Main finding

As reported in the abstract

Baseline disease activity (DAPSA score)
Mean DAPSA score (moderate disease activity)
19±14
Mean swollen joint count
2.1±3.2
Mean tender joint count
6.0±8.0
Initially involved joints: hands
40%
Initially involved joints: knees
28%
Entheseal pain
39%
Dactylitis
27%
Obesity
27%
At least one CV risk factor or disease
49%

Observational data: associations, not effects.

Original publication

Early peripheral psoriatic arthritis: Baseline features of the first 186 patients in the French Nationwide APACHE Cohort. Joint Bone Spine. Published 27 May 2025. doi:10.1016/j.jbspin.2025.105930

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