Duration of effect in treatment of methotrexate intolerance in juvenile idiopathic arthritis using Eye Movement Desensitization and Reprocessing (EMDR) can be improved by Bi-lateral Alternating Stimulation Tactile (BLAST) wristbands
Authors' conclusion
Treatment with Eye Movement Desensitization and Reprocessing (EMDR) could present an effective treatment of MTX intolerance, and using BLAST wristbands, further potential improvement is possible.
Study context
- Population
- Consecutive patients with juvenile idiopathic arthritis (JIA) and signs of methotrexate (MTX) intolerance admitted to the German Center for Pediatric and Adolescent Rheumatology, October 2016 to March 2024
- Participants
- 87 patients
- Exposure
- EMDR plus BLAST wristbands vs EMDR without BLAST wristbands
- Group 1n = 53reference
- Group 2n = 34
- Outcome
- MTX intolerance (MISS) over time
- Follow-up
- Before and after treatment, 4 and 12 months after treatment
Methodological detailsconsecutive patients, single-centre, sequential (initial patients EMDR, subsequent patients additionally BLAST wristbands)
- Consecutive patients
- Single-centre
- Sequential (initial patients EMDR, subsequent patients additionally BLAST wristbands)
Main finding
MISS score, mean · before treatment
Repeated measures ANOVA, MISS over time
F(3,114) = 64.6
P < 0.001
By group
Group 1
15.0
mean · SD 5.5
Group 2
16.8
mean · SD 5.6
As reported in the abstract
Observational data: associations, not effects.
Further findings
MISS results over time (repeated measures ANOVA)
- Significant difference between the MISS results over time, F(3,114) = 64.6
- P < 0.001
Parts of this Brief are withheld: the automatic checks could not confirm them against the abstract.
Original publication
Duration of effect in treatment of methotrexate intolerance in juvenile idiopathic arthritis using Eye Movement Desensitization and Reprocessing (EMDR) can be improved by Bi-lateral Alternating Stimulation Tactile (BLAST) wristbands. Pediatr Rheumatol Online J. Published 24 October 2024. doi:10.
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