Sjögren's disease & overlap diseases
Does lacrimal gland ultrasound discriminate between Sjögren’s disease and non-Sjögren’s sicca patients?
Authors' conclusion
LGUS CD demonstrated similar characteristics in SjD and non-SjD sicca patients, suggesting limited discriminatory value.
Study context
- Population
- Patients with clinically suspected Sjögren's disease (SjD)
- Participants
- 40 patients
- Comparison
- LGUS CD vs 2016 ACR/EULAR classification criteria for SjD
- SjDn = 23
- non-SjD siccan = 17reference
- Outcome
- Sensitivity and specificity of LGUS CD to predict SjD classification according to 2016 ACR/EULAR criteria
Methodological detailsroutine clinical practice conditions
- Routine clinical practice conditions
Performance
As reported in the abstract
LGUS CD performance for SjD classification
| Test or model | Sensitivity | Specificity |
|---|---|---|
| LGUS CD | 57% | 53% |
LGUS CD
Sensitivity57%
Specificity53%
Further findings
Total and individual-eye LGUS CD scores
- Did not differ significantly between SjD and non-SjD sicca patients
ACR/EULAR classification criteria by high vs low LGUS CD score
- None differed significantly between high and low LGUS CD score groups
Correlation between LGUS CD and ocular function tests (construct validity)
- Poor correlations (Spearman ρ)
- 0.028-0.187
Original publication
Does lacrimal gland ultrasound discriminate between Sjögren’s disease and non-Sjögren’s sicca patients? Scand J Rheumatol. Published 17 April 2026. doi:10.
Composed by AI from the published abstract and checked against it. How Briefs are made →