Rheumatoid arthritis

Disease Activity and Health‐Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits

Arthritis RheumatolPublished Prospective cohort study

Authors' conclusion

Alcohol consumption was associated with lower disease activity and higher health-related quality of life in RA patients in a dose-dependent manner.

Study context

Population
Patients with newly diagnosed rheumatoid arthritis (RA) from the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) population-based case-control study
Participants
1,228 patients
Exposure
Drinkers vs non-drinkers
Outcome
Unfavorable outcomes regarding disease activity and health-related quality of life
Follow-up
1 year
Methodological detailsfollow-up of a population-based case-control study (EIRA), logistic regression
  • Follow-up of a population-based case-control study (EIRA)
  • Logistic regression

Main finding

As reported in the abstract

1 year of follow-up
  • Non-drinkers at baseline had higher disease activity and more severe pain vs drinkers
  • At 1 year, non-drinkers reported higher swollen and tender joint counts, more pain and fatigue, lower global health scores and lower health-related quality of life

Observational data: associations, not effects.

Further findings

Drinkers vs non-drinkers who had not changed alcohol habits at or after the year of disease onset

Inverse relationship between alcohol consumption and RA-specific outcomes also observed

Stopped drinking postbaseline vs drinkers · 1 year of follow-up

Higher disease activity, more pain and lower health-related quality of life in those who stopped drinking; no difference in baseline disease activity between continued vs discontinued drinkers

Original publication

Disease Activity and Health‐Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits. Arthritis Rheumatol. Published 12 April 2023. doi:10.1002/art.42442

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