Disease Activity and Health‐Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits
Authors' conclusion
Alcohol consumption was associated with lower disease activity and higher health-related quality of life in RA patients in a dose-dependent manner.
Study context
- Population
- Patients with newly diagnosed rheumatoid arthritis (RA) from the Epidemiological Investigation of Rheumatoid Arthritis (EIRA) population-based case-control study
- Participants
- 1,228 patients
- Exposure
- Drinkers vs non-drinkers
- Outcome
- Unfavorable outcomes regarding disease activity and health-related quality of life
- Follow-up
- 1 year
Methodological detailsfollow-up of a population-based case-control study (EIRA), logistic regression
- Follow-up of a population-based case-control study (EIRA)
- Logistic regression
Main finding
As reported in the abstract
1 year of follow-up
- Non-drinkers at baseline had higher disease activity and more severe pain vs drinkers
- At 1 year, non-drinkers reported higher swollen and tender joint counts, more pain and fatigue, lower global health scores and lower health-related quality of life
Observational data: associations, not effects.
Further findings
Drinkers vs non-drinkers who had not changed alcohol habits at or after the year of disease onset
- Inverse relationship between alcohol consumption and RA-specific outcomes also observed
Stopped drinking postbaseline vs drinkers · 1 year of follow-up
- Higher disease activity, more pain and lower health-related quality of life in those who stopped drinking; no difference in baseline disease activity between continued vs discontinued drinkers
Original publication
Disease Activity and Health‐Related Quality of Life Among Patients With Rheumatoid Arthritis With Different Alcohol Consumption Habits. Arthritis Rheumatol. Published 12 April 2023. doi:10. 1002/ art. 42442
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