Rheumatoid arthritis

Direct and indirect costs of rheumatoid arthritis and related conditions in France: a 2015–2023 nation-wide population-based study

Joint Bone SpinePublished Retrospective population-based study

Authors' conclusion

The economic burden of RA in France has grown substantially, with a shift toward higher medication and indirect costs.

Study context

Population
Patients with rheumatoid arthritis (RA) or related conditions in France, 2015–2023, identified in the SNDS (nearly the entire French population)334,290 patients in 2023
Outcome
Evolution of direct and indirect costs of RA and related conditions (annual reimbursed expenditures)
Follow-up
2015–2023
Methodological detailsnation-wide, National Health Data System (SNDS), validated algorithms
  • Nation-wide
  • National Health Data System (SNDS)
  • Validated algorithms

Main finding

As reported in the abstract

Annual costs of RA, 2015 to 2023
Number of patients with RA, 2015 to 2023 (+26%)
265,270 to 334,290
Total reimbursed expenditures
€885.9 million to €1118.3 million
Mean cost per patient per year (stable), 2023
€3345
Medication costs, 2015 to 2023 (+39%)
€404.3 million to €563.9 million
Indirect costs: second largest component from 2020 onward; increase over study period
+48%

Observational data: associations, not effects.

Original publication

Direct and indirect costs of rheumatoid arthritis and related conditions in France: a 2015–2023 nation-wide population-based study. Joint Bone Spine. Published 11 July 2026. doi:10.1016/j.jbspin.2026.106099

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