Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients
Authors' conclusion
Age- and bone-specific ADC reference values were established and effectively differentiated normal from inflammatory SIJ signals.
Study context
- Population
- Skeletally immature youth undergoing sacroiliac joint (SIJ) imaging with diffusion-weighted imaging (DWI)86 reference youth
- Comparison
- Apparent diffusion coefficient (ADC) values of normal vs inflammatory SIJ signals in pediatric patients
- Referencen = 86reference
- Outcome
- Normative pediatric ADC values and thresholds distinguishing normal from inflammatory SIJ signals (AUROC, specificity)
Methodological detailsnormative reference values, within-patient clustering accounted for
- Normative reference values
- Within-patient clustering accounted for
Performance
As reported in the abstract
ADC thresholds distinguishing normal from inflammatory SIJ signals
Most iliac regions, area under the receiver operating characteristic (AUROC)
≥0.90
Peripubertal inferior ilium, AUROC
0.78
Sacral thresholds, AUROC
≥ 0.77
Sacral, prepubertal group, AUROC
0.68
Further findings
Normative ADC values by region and age
- Inferior ilium ADC higher than mid and superior regions in all immature age groups
- all P < 0.0001
- Inferior ilium ADC decreased with age
- P = 0.0001
- Sacral ADC declined with age
- P = 0.0001
- No age trend in superior or mid ilium
- P = 0.14
Original publication
Diffusion‐Weighted Imaging for the Evaluation of the Sacroiliac Joint in Pediatric Patients. Arthritis Care Res (Hoboken). Published 20 January 2026. doi:10.
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