Vasculitis & polymyalgia rheumatica
Diffuse generalized venulitis as the primary pathology of Behçet's disease: A comprehensive magnetic resonance venography study
Authors' conclusion
The results of our study suggest that the involvement of the venous system is diffuse and generalized in BD, and demonstration of venulitis might help diagnose the disease.
Study context
- Population
- Behçet's Disease (BD) patients fulfilling the International Study Group (ISG) criteria (mean age 39.3 ± 11.3 years; 48 [73.8%] male) and healthy controls65 BD patients · 20 controls
- Participants
- 33 / 32 / 20
- Exposure
- BD patients vs healthy controls
- Vascular BDn = 33
- Non-vascular BDn = 32
- Healthy controlsn = 20reference
- Outcome
- Vein wall thickening on MR venography (inferior vena cava (IVC), common iliac veins (CIV), EIV, IIV, common femoral veins (CFV), femoral veins (FV), greater saphenous veins (GSV))
Methodological detailsMagnetic resonance (MR) venography and ultrasonography, healthy control comparison
- MR venography and ultrasonography
- Healthy control comparison
Main finding
As reported in the abstract
- BD vs Healthy controls: P < 0.05 for all vein segments
Observational data: associations, not effects.
Further findings
Perivascular findings on MR venography (contrast enhancement, enlarged lymph nodes, seminal vesicle vascularization)
- Remarkably more frequent in vascular BD than non-vascular BD and healthy controls
Original publication
Diffuse generalized venulitis as the primary pathology of Behçet's disease: A comprehensive magnetic resonance venography study. Semin Arthritis Rheum. Published 9 August 2023. doi:10.
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