Vasculitis & polymyalgia rheumatica
ABO blood groups and increased risk for the development of vascular involvement in Behçet's disease
Authors' conclusion
The results of this preliminary study show the potential contribution of ABO blood groups to the vascular-BD phenotype and suggest an increased risk for vascular BD in association with non-O blood groups.
Study context
- Population
- Behçet's disease (BD) patients meeting the ISG criteria with available ABO blood group data
- Participants
- 411 patients
- Exposure
- Non-O vs O blood groups
- On = 143reference
- Non-On = 268
- Outcome
- Vascular involvement in BD
Main finding
As reported in the abstract
Vascular involvement
- Vascular involvement significantly more frequent and risk for overall vascular and venous events up to 2-fold higher with non-O groups
- After adjustment for age, sex and comorbidities, risk for arterial disease also increased with non-O groups
- ABO blood groups independent risk factors for vascular BD in multiple regression models
- Blood group B had a higher risk for vascular events than other non-O groups
Observational data: associations, not effects.
Original publication
ABO blood groups and increased risk for the development of vascular involvement in Behçet's disease. Clin Exp Rheumatol. Published 15 October 2024. doi:10.
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